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Seek prompt evaluation if you notice jaundice (yellowing of the skin or eyes), dark urine, pale stools, severe fatigue, right upper-abdominal pain, or unexplained nausea

B12 deficiency can increase the risk of birth defects and may contribute to premature birth or miscarriage

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Biochem J 1921;15(2):286

Vitamin B-12 is the source of coenzymes for the respective methylation of homocysteine by 5-methyltetrahydrofolate (5-methylTHF) to form methionine and for the mitochondrial conversion of methylmalonyl-CoA to succinyl-CoA ( Figure 1 )

It is always wise to consult with a healthcare provider, especially if you have a history of renal issues or are taking medication